(Diseases)
This page provides everything you need to know about Cholestasis of Pregnancy.
What is Cholestasis of Pregnancy?
It is a liver condition caused by the accumulation of bile in the liver and bloodstream, leading to intense itching during the third trimester of pregnancy. It is also known as cholestasis during pregnancy or obstetric cholestasis.
Bile is a substance produced by the liver and stored in the gallbladder. Every time you eat, this substance breaks down fats so they can be properly digested.
What are the symptoms of Cholestasis of Pregnancy?
Severe itching, which is the most common and primary symptom.
Nausea.
Dark urine.
Pale gray or light brown stool.
Extreme fatigue.
Loss of appetite.
Pain in the upper right side of the abdomen.
Jaundice.
What are the causes of Cholestasis of Pregnancy?
Cholestasis of pregnancy typically develops in the third trimester. The increased levels of estrogen and progesterone during pregnancy affect the liver’s ability to transport bile.
This means the bile does not move properly through the body, leading to its buildup in the liver and entry into the bloodstream.
How is it diagnosed?
The doctor will take a medical history and perform a physical examination, and may request additional procedures as needed, such as:
Blood tests.
Liver and bile duct ultrasound.
What are the treatment options for Cholestasis of Pregnancy?
Treatment involves various measures depending on the need, and may include:
Symptom management treatments:
Anti-itch medications (consult your doctor).
Wearing soft, loose clothing.
Rest.
How can Cholestasis of Pregnancy be prevented?
There are no known ways to prevent cholestasis of pregnancy.
What are the complications of Cholestasis of Pregnancy?
For the mother:
Problems absorbing vitamin K.
Gestational diabetes.
For the fetus:
Preterm birth.
Stillbirth (fetal death in the womb).
When should you see a doctor?
You should consult your doctor if you experience severe itching that does not go away during pregnancy, or if your skin or the whites of your eyes appear yellow.
Frequently Asked Question:
Does the condition persist after delivery? In most cases, the body returns to normal due to the return of hormone levels to their normal state.
